Below is a compilation of all of the research papers and academic works being used to conduct a clinical trial investigating insulin resistance and atherosclerotic cardiovascular disease using Ganoderma lucidum.

Chan, S. W., Tomlinson, B., Chan, P., & Lam, C. W. K. (2021). The beneficial effects of Ganoderma lucidum on cardiovascular and metabolic disease risk. Pharmaceutical Biology, 59(1), 1159–1169. https://doi.org/10.1080/13880209.2021.1969413

Heriansyah, T., Nurwidyaningtyas, W., Sargowo, D., Tjahjono, C. T., & Wihastuti, T. A. (2019). Polysaccharide peptide (PsP) Ganoderma lucidum: A potential inducer for vascular repair in type 2 diabetes mellitus model. Vascular Health and Risk Management, Volume 15, 419–427. https://doi.org/10.2147/VHRM.S205996

Klupp, N. L., Chang, D., Hawke, F., Kiat, H., Cao, H., Grant, S. J., & Bensoussan, A. (n.d.). Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors—Klupp, NL – 2015 | Cochrane Library. Retrieved January 7, 2025, from https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD007259.pub2/full

Klupp, N. L., Chang, D., Hawke, F., Kiat, H., Cao, H., Grant, S. J., & Bensoussan, A. (2015). Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database of Systematic Reviews, 2021(9). https://doi.org/10.1002/14651858.CD007259.pub2

Lee, H. A., Cho, J.-H., Afinanisa, Q., An, G.-H., Han, J.-G., Kang, H. J., Choi, S. H., & Seong, H.-A. (2020). Ganoderma lucidum Extract Reduces Insulin Resistance by Enhancing AMPK Activation in High-Fat Diet-Induced Obese Mice. Nutrients, 12(11), 3338. https://doi.org/10.3390/nu12113338

Xu, S., Dou, Y., Ye, B., Wu, Q., Wang, Y., Hu, M., Ma, F., Rong, X., & Guo, J. (2017). Ganoderma lucidum polysaccharides improve insulin sensitivity by regulating inflammatory cytokines and gut microbiota composition in mice. Journal of Functional Foods, 38, 545–552. https://doi.org/10.1016/j.jff.2017.09.032

Yang, Z., Wu, F., He, Y., Zhang, Q., Zhang, Y., Zhou, G., Yang, H., & Zhou, P. (2018). A novel PTP1B inhibitor extracted from Ganoderma lucidum ameliorates insulin resistance by regulating IRS1-GLUT4 cascades in the insulin signaling pathway. Food & Function, 9(1), 397–406. https://doi.org/10.1039/C7FO01489A

 

 

 

 

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